2-Decarboxy-2-aminomethyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 com

Details 2-Decarboxy-2-aminomethyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 com 2-Decarboxy-2-aminomethyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 com

1979-09-07

1981-03-31

Chan, Nicky

Harness for working animal

2603452, 542429, C07D30793

Patent

active

042594790

ABSTRACT:
The present invention relates to novel 2-decarboxy-2-aminomethyl-4-halo-5,9-epoxy-9-deoxy-PGF.sub.1 compounds, which are intermediates useful for the preparation of corresponding 5,9.alpha.-epoxy-9-deoxy-PGF.sub.1 and 5,9-epoxy-9-deoxy-4,5-didehydro-PGF.sub.1 compounds. These end products are employed for induction of a variety of prostacyclinlike pharmacological effects. Accordingly, these end products are useful pharmacological agents for the same purposes for which prostacyclin is employed.

REFERENCES:
patent: 4125713 (1978-11-01), Nelson
patent: 4158667 (1979-06-01), Axen

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