2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI.sub.

Details 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI.sub. 2-Decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI.sub.

1980-03-03

1981-03-17

Doll, John

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

564428, 564453, 564454, 564460, C07C 8734, C07C 8740, C07C 87451, C07C 87453

Patent

active

042566673

ABSTRACT:
The present invention provides novel 2-decarboxy-2-aminomethyl-19-hydroxy-19-methyl-6a-carba-PGI.sub.1 compounds which are useful for pharmacological purposes, e.g., anti-asthmatic indications.

REFERENCES:
patent: 3849474 (1974-11-01), Abraham et al.
patent: 3919285 (1975-11-01), Axen
patent: 3935240 (1976-01-01), Mallion
patent: 3954741 (1976-05-01), Schaaf et al.
patent: 4064351 (1977-12-01), Sukai et al.
Johnson, "Jacs", 100, pp. 7690-7704, (1978).

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