Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-09-27
2005-09-27
McKane, Joseph K. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S311000, C514S314000, C514S354000, C514S422000, C514S446000, C546S113000, C546S152000, C546S176000, C546S280400, C549S065000
Reexamination Certificate
active
06949563
ABSTRACT:
Compounds represented by Formula (I):or a pharmaceutically acceptable salt or N-oxide thereof, wherein R1 isR2 isand R3 is C0-4alkyl, are useful in the treatment of cancer.
REFERENCES:
patent: 5968965 (1999-10-01), Dinsmore et al.
patent: 6140351 (2000-10-01), Arnaiz et al.
patent: 6187799 (2001-02-01), Wood et al.
patent: 6207693 (2001-03-01), Setoi et al.
patent: 6316482 (2001-11-01), Setoi et al.
patent: 6376515 (2002-04-01), Zhu et al.
patent: 6410561 (2002-06-01), Shinkai et al.
patent: 6448277 (2002-09-01), Altmann et al.
patent: 0 832 061 (1998-04-01), None
patent: WO 99/032477 (1999-07-01), None
patent: WO 00/027819 (2000-05-01), None
patent: WO 00/027820 (2000-05-01), None
patent: WO 02/066470 (2000-08-01), None
patent: WO 01/05763 (2001-01-01), None
patent: WO 01/007050 (2001-02-01), None
patent: WO 01/019798 (2001-03-01), None
patent: WO 01/064642 (2001-09-01), None
patent: WO 02/000651 (2002-01-01), None
patent: WO 02/055501 (2002-07-01), None
patent: WO 02/068406 (2002-09-01), None
Lala, P.K. et al., Cancer and Metastasis Reviews (1998), 17(1), 91-106.
Golub, T.R. et al., Science (1999), vol. 286, 531-537.
Sihto, Harri et al., “KIT and Platlet-Derived Growth Factor Receptor Alpha Tyrosine Kinase Gene Mutations and KIT Amplifications in Human Solid Tumors,” Journal of Clinical Oncology, vol. 23(1), 2005, pp. 49-57.
Potti, Anil et al., “Immunohistochemical Determination of HER-2
eu Overexpression in Malignant Melanoma Reveals No Prognostic Value, while c-KIT Overexpression Exhibits Potential Therapeutic Implications,” Journal of Carcinogenesis, vol. 2(8), 2003.
Ahmed Saleh
Castelhano Arlindo Lucas
Crew Andrew Phillip
Dawson Graham
Doyle Kevin
Lee Shu M.
Lee Susannah E.
McKane Joseph K.
Stewart Alexander
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