2-Carbamoyl-1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones

Details 2-Carbamoyl-1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones 2-Carbamoyl-1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones

1977-07-27

1978-03-21

Jiles, Henry R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

2602393B, 42424854, C07D22316, C07D41306, A61K 3155

Patent

active

040804500

ABSTRACT:
New physiologically active 2-carbamoyl-1,2,4,5-tetrahydro-3H-2-benzazepin-3-ones having the general formula ##STR1## wherein R.sub.1 is hydrogen or phenyl, R.sub.2 is morpholino or amino mono- or di-substituted by C.sub.1 -C.sub.4 -alkyl, C.sub.5 -C.sub.6 -cycloalkyl or phenyl, R.sub.4 is hydrogen or C.sub.1 -C.sub.4 -alkyl, R.sub.5 is hydrogen or C.sub.1 -C.sub.4 -alkyl, R.sub.7 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkoxy, R.sub.8 is hydrogen, halogen or C.sub.1 -C.sub.4 -alkyl, processes for the preparation thereof and pharmaceutical compositions containing the same. In particular, the compounds of this invention are useful in the treatment of memory disorders.

REFERENCES:
wittekind et al., "J. Het. Chem." vol. 8, pp. 495-501 (1971).

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