2-butyl-3-(4-[3(dibutylamino)propoxy]benzoyl)-5-nitro-benzof...

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

Reexamination Certificate

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C560S023000, C562S444000

Reexamination Certificate

active

06846936

ABSTRACT:
The invention relates to 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl-5-nitrobenzofuran hydrochloride, to its preparation and to its use as synthetic intermediate, in particular in preparing 2-butyl-3-(4-[3-(dibutylamino)propoxy]benzoyl)-5-nitrobenzofuran, itself an intermediate for dronedarone.

REFERENCES:
patent: 5223510 (1993-06-01), Gubin et al.
patent: 0 471 609 (1992-02-01), None
Gutan, AL, ‘Process for the preparation of dronedarone’ CA 138:385296 (2003).*
Fino, N, ‘A process for the preparation of 2-butyl-5-[mmethansulfonamido]benzofuran as an intermediate for the synthesis of dronedarone’ CA 137:33205 (2002).*
Y. Oshishi et al; “Antibacterial activity and Polarographic Half-Wave Reduction Potential of 2-Nitrobenzo 'b!furans”; Chem. Pharm. Bull; vol. 33, No. 7, 1985, pp2854-2861; XP00156510.

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