Organic compounds -- part of the class 532-570 series – Organic compounds – Carboxylic acid esters
Reexamination Certificate
2006-08-29
2008-08-05
Anderson, Rebecca L (Department: 1626)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carboxylic acid esters
C562S458000, C548S228000
Reexamination Certificate
active
07408076
ABSTRACT:
Disclosed are 2-bromoaniline or 2-chloroaniline compounds of formula (I):wherein R, R1and X are as defined. The compounds are useful as intermediates for preparing indole compounds.
REFERENCES:
patent: 427251 (1935-04-01), None
Edwards et al. (CAS Abstract and Structure From) Journal of the Chemical Society, Transactions 1912, 101, 1376-89.
Ressy et al. (Bull. Soc. Chim. 1923, 33, 1297-9); CAS printout attached.
Eller et al. (Berichte der Deutschen Chemischen Gesellschaft [Abteilung] B: Abhandlungen 1922, 55B, 217-24); CAS printout attached.
Wheeler et al. (J. Amer. Chem. Soc. 1909, 31, 937-43); CAS printout attached.
Hodgson et al. (J. Chem. Soc. 1926, 542-6); CAS printout attached.
Bermudez et al. (Bioorganic & Med. Chem. Lett. 1992, 2(6), 519-22); CAS abstract attached.
R.C. Larock, et al. “Synthesis of 2,3-Disubstituted Indoles via Palladium-Catalyzed Annulation of Internal Alkynes”, Journal of Organic Chemistry, 1998, vol. 63, pp. 7652-7662.
F. Maassarani, et al. “Controlled Synthesis of Heterocyclic Compounds through Ring Enlargement by Alkyne Insertions into the Pd-C Bonds of Cyclopalladated Amines Followed by Subsequent Ring Closure”, Organometallics, 1987, vol. 6, pp. 2029-2043 XP-002375383.
F. Maassarani, et al. “Stepwise Insertion of One, Two, and Three Alkyne Molecules into the Pd-C Bond of a Six-Membered Palladocycle. One-Pot Synthesis of Spirocyclic Compounds”, Organometallics, 1987, vol. 6, pp. 2043-2053 XP-002375384.
F. Maassarani, et al., “Selective hetero- and carbo-cycle synthesis via masked cyclopalladated secondary amine and ketone functions”, J. Organometallic Chemistry, vol. 466, 1994, pp. 265-271 XP-002375385.
Database Zregistry [Online]Dec. 12, 1987, XP002377297 retrieved from STN RN: 111783-46-1 Abstract.
Database Zregistry [Online] Nov. 16, 1984, XP002377298, retrieved from STN RN: 2486-71-7 Abstract.
Database Zregistry [Online]Nov. 16, 1984, XP002377299, retrieved from STN RN: 95-74-9 Abstract.
M. Shen, et al. “The First Regioselective Palladium-Catalyzed Indolization of 2-Bromo- or 2-Chloroanilines with Internal Alkynes: A New Approach to 2,3-Disubstituted Indoles”, Organic Letters, vol. 6, No. 22, pp. 4129-4132 XP-002375386, 2004.
Li Guisheng
Liu Jianxiu
Lu Zhi-Hui
Roschangar Frank
Senanayake Chris Hugh
Anderson Rebecca L
Boehringer Ingelheim International GmbH
Devlin Mary-Ellen M.
Dow David A.
Morris Michael P.
LandOfFree
2-Bromoanaline and 2-chloroaniline compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-Bromoanaline and 2-chloroaniline compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-Bromoanaline and 2-chloroaniline compounds will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4001469