2-.beta.-D-ribofuranosylselenazole-4-carboxamide compounds

Details 2-.beta.-D-ribofuranosylselenazole-4-carboxamide compounds 2-.beta.-D-ribofuranosylselenazole-4-carboxamide compounds

1983-02-15

1985-07-23

Brown, Johnnie R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Carbohydrates or derivatives

536 53, 536 28, 536 29, C07H 1924

Patent

active

045310017

ABSTRACT:
A class of novel 2-.beta.-D-ribofuranosylselenazole-4-carboxamide nucleoside and nucleotide compounds and methods for their production are provided. Compounds of the class typically have pharmacological properties, especially antitumor and antiviral properties, and are well tolerated, being useful, for example, in treating tumors and viral infections in warm blooded animals.

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Srivastava et al., Journal of Medicinal Chemistry, 1977, vol. 20, No. 2, pp. 256-262.
Srivastava et al., J. Med. Chem., 1983, vol. 26, pp. 445-448.
Earle et al., Cancer Research, 1983, vol. 43, pp. 133-137.

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