2.beta.-Chloromethyl-2.alpha.-methylpenam-3.alpha.-carboxylic ac

Details 2.beta.-Chloromethyl-2.alpha.-methylpenam-3.alpha.-carboxylic ac 2.beta.-Chloromethyl-2.alpha.-methylpenam-3.alpha.-carboxylic ac

1983-04-12

1984-04-24

Hollrah, Glennon H.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424271, 2602452R, C07D49932

Patent

active

044446870

ABSTRACT:
2.beta.-Chloromethyl-2.alpha.-methylpenam-3.alpha.-carboxylic acid sulfone and salts and esters thereof were synthesized and found to be potent inhibitors of .beta.-lactamases.

REFERENCES:
patent: 4287181 (1981-09-01), Kellogg
patent: 4309347 (1982-01-01), Bigham
patent: 4342772 (1982-08-01), Godtfredsen et al.
Journal of Medicinal Chemistry, 1981, 24, 1531-1534.

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