2-benzyl-4-sulfonyl-4H-isoquinolin-1,3-diones and their use as a

Details 2-benzyl-4-sulfonyl-4H-isoquinolin-1,3-diones and their use as a 2-benzyl-4-sulfonyl-4H-isoquinolin-1,3-diones and their use as a

1997-05-13

1998-04-21

Berch, Mark L.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546142, C07D21722, A61K 3147

Patent

active

057417989

ABSTRACT:
Antiinflammatory compounds of the formula I or IA ##STR1## wherein, R.sub.1 is hydrogen, halogen, C.sub.1-4 alkyl, or C.sub.1-4 alkoxy;
R.sub.2 and R.sub.3 are the same or different and each is hydrogen, halogen, trifluoromethyl, C.sub.1-4 alkyl, or C.sub.1-4 alkoxy; and,
R.sub.4 is C.sub.3-4 alkyl, C.sub.1-4 -trifluoroethyl, 2-thienyl, 2-naphthyl, phenyl or phenyl mono- or disubstituted with C.sub.1-4 alkyl, C.sub.1-4 alkoxy, halogen, trifluoromethyl, or nitro.

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