Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2007-12-11
2007-12-11
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S502000
Reexamination Certificate
active
10725349
ABSTRACT:
Novel compounds of the formula Iin whichR, X, n and m are as defined herein are inhibitors of tyrosine kinase and can be employed for the treatment of tumours, for neuroprotection and for protection of the stress proteins of the skin.
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Cherrington et al , New paradigms for the treatment of cancer: the role of antiangiogenesis agents. PMID: 10818676.
Kim et al, Epidermal growth factor receptor biologh (IMC-C 225), PMID :11673692.
Jafri, Mechanisms of metastasis as related to receptor tyrosine kinase in small-cell lung cancer, PMID: 14529091 (2003).
Yamamura et al. “Skin compositions . . . ” CA 139:369359 (2003).
Belcour et al. “Cosmetic compositions . . . ” CA 122:114661 (1995).
Buchholz Herwig
Carola Christophe
Mujica-Fernaud Teresa
Rautenberg Wilfried
Sirrenberg Christian
Chang Celia
Merck Patent GmbH
Millen, White, Zelano & Branican
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