2-Azabicyclo[3.3.1]nonane derivatives

Details 2-Azabicyclo[3.3.1]nonane derivatives 2-Azabicyclo[3.3.1]nonane derivatives

2006-06-06

2006-06-06

Aulakh, Charanjit S. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C546S112000

Reexamination Certificate

active

07056930

ABSTRACT:
The subject invention relates to 2-azabicyclo[3.3.1]nonane derivatives, pharmaceutical compositions comprising such derivatives and methods of using such derivatives to treat disease states, disorders and conditions mediated by opioid receptors. The subject invention also particularly relates to using such derivatives to treat certain disorders and conditions, for example irritable bowel syndrome, drug addiction, including alcohol addiction, depression, anxiety, schizophrenia and eating disorders, among others, as are more fully described herein.

REFERENCES:
patent: 2143145 (1939-06-01), Farnsworth
May et al.: “Structures Related to Morphine. II. An Isomer of N-Methylmorphinan” J. Org. Chem., vol. 19, No. 4, 1954, pp. 618-6222, XP002291306, Compound VI.
May: “Structures Related to Morphine. VI. N-Phenylethyl Derivatives of Some Phenyl- And Benz-Morphans” J. Org. Chem., vol. 21, No. 8, 1956, pp. 899-901, XP002291307. Cpd. Ila.
Froimowitz M. et al.: “Phenylmorphans and Analogues: Opioid Receptor Subtype Selectivitiy and Effect of Conformation on Activity”, Journal of Medicinal Chemistry, American Chemical Society. Washington, US, vol. 35, No. 9, 1992, pp. 1521-1525, XP002203667, ISSN: 0022-2623 The Whole Document.
Thomas J B et al.: “N-Substituted 9. Beta. -Methyl-5-(3-Hydroxyphenyl)Morphans Are Opioid Receptor Pure Antagonists” Journal of Medicinal Chemistry, American Chemical Society, Washington, US, vol. 41, No. 21, 1998, pp. 4143-4149, XP002203671. ISSN: 0022-2623. The Whole Document.

Affiliated with

Also associated with

Rating

2-Azabicyclo[3.3.1]nonane derivatives does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-Azabicyclo[3.3.1]nonane derivatives, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-Azabicyclo[3.3.1]nonane derivatives will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3626686