Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1983-05-09
1984-10-16
Daus, Donald G.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
544236, 544350, A61K 31495, C07D48700
Patent
active
044774540
ABSTRACT:
2-Aryltetraazaindenes of the formula ##STR1## wherein --A-- is --N.dbd.CH--CH.dbd.N-- or --CH.dbd.N--N.dbd.CH--, Ar is unsubstituted phenyl or phenyl mono-, di- or tri-substituted by hydroxyl, mercapto, dialkylamino, trifluoromethyl and/or --Z--R groups, Z is --O--, --S-- or --SO-- and R is alkyl, alkenyl, alkynyl or cyanomethyl, the alkyl, alkenyl and alkynyl groups each having up to 5 C atoms, and their physiologically acceptable salts, exhibit blood pressure, myocardial contraction, and anti-ulcer activities.
REFERENCES:
patent: 3244715 (1966-04-01), Castle
patent: 3660397 (1972-05-01), Jones et al.
patent: 4072746 (1978-02-01), Lesher et al.
patent: 4327100 (1982-04-01), Austel et al.
Arzneimittelforschung, vol. 31 (I) No. 1a (1981, pp. 141 to 278.
Enenkel Hans J.
Harting Juergen
Jonas Rochus
Kloft Michael
Minck Klaus-Otto
Daus Donald G.
Merck Patent Gesellschaft mit beschrankter Haftung
Shen Cecilia
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