2-aryl thiazole derivatives as KCNQ modulators

Details 2-aryl thiazole derivatives as KCNQ modulators 2-aryl thiazole derivatives as KCNQ modulators

2007-09-25

2007-09-25

Morris, Patricia L. (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C514S342000, C514S365000, C546S124000, C546S270400, C548S200000

Reexamination Certificate

active

10731854

ABSTRACT:
Novel 2-arylthiazole derivatives of Formula I are described which are openers of KCNQ potassium channels and are useful in the treatment of disorders that are responsive to the opening of the KCNQ potassium channels, including pain and migraine

REFERENCES:
patent: 3689481 (1972-09-01), Scheuermann et al.
patent: 3794636 (1974-02-01), Girgis
patent: 3872124 (1975-03-01), LeMartret et al.
patent: 4923886 (1990-05-01), Shiokawa et al.
patent: 4980363 (1990-12-01), Shimotori et al.
patent: 5057142 (1991-10-01), Baasner et al.
patent: 5244867 (1993-09-01), Ditrich et al.
patent: 5614520 (1997-03-01), Kondo et al.
patent: 5846990 (1998-12-01), Murugesan et al.
patent: 5859035 (1999-01-01), Anthony et al.
patent: 5888941 (1999-03-01), Bartroli et al.
patent: 5998450 (1999-12-01), Eicken et al.
patent: 6518290 (2003-02-01), Sierra
patent: 57183768 (1982-11-01), None
patent: 01250379 (1989-10-01), None
patent: 02229190 (1990-09-01), None
patent: 04049290 (1992-02-01), None
patent: 4-128275 (1992-04-01), None
patent: 128275 (1992-04-01), None
patent: 04128275 (1992-04-01), None
patent: WO 95/19972 (1995-07-01), None
patent: WO 98/28282 (1998-07-01), None
patent: WO 99/59570 (1999-11-01), None
patent: WO 99/66925 (1999-12-01), None
patent: WO 00/06085 (2000-02-01), None
patent: WO 01/10798 (2001-02-01), None
patent: WO 01/40207 (2001-06-01), None
H.-S. Wang, et al, “KCNQ2 and KCNQ3 Potassium Channel Subunits: Molecular Correlates of the M-Channel,” Science, 282, pp. 1890-1893, 1998.

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