Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2005-10-18
2010-02-09
Shameem, Golam M (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C548S125000, C548S131000, C548S240000, C548S251000, C548S255000, C546S268100, C546S268400, C546S269400, C544S224000, C544S242000, C544S336000, C514S361000, C514S378000, C514S381000, C514S385000
Reexamination Certificate
active
07659294
ABSTRACT:
The present invention encompasses compounds of Formula I:as well as the pharmaceutically acceptable salts thereof. The compounds are S1P1/Edg1 receptor agonists and thus have immunosuppressive, anti-inflammatory and hemostatic activities by modulating leukocyte trafficking, sequestering lymphocytes in secondary lymphoid tissues, and enhancing vascular integrity. The invention is also directed to pharmaceutical compositions containing such compounds and methods of treatment or prevention.
REFERENCES:
patent: 6720343 (2004-04-01), Yoshioka et al.
Hale Jeffrey John
Yan Lin
Camara Valerie J.
Merck & Co. , Inc.
Shameem Golam M
Zhao Yong
LandOfFree
2-(aryl)azacyclylmethyl carboxylates, sulfonates,... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with 2-(aryl)azacyclylmethyl carboxylates, sulfonates,..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-(aryl)azacyclylmethyl carboxylates, sulfonates,... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4189385