Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Patent
1984-11-05
1987-05-19
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
544321, C07D23947, A61K 31505
Patent
active
046669159
ABSTRACT:
2-Anilino-1,6-dihydro-6-oxo-5-pyrimidinecarboxylic acid derivatives of the formula: ##STR1## wherein R.sup.1 and R.sup.2 are the same or different and are each hydrogen, an alkoxy, a tetrahydrofurylalkoxy, an alkyl, an alkoxycarbonyl, a halogen, a dialkylamino, hydroxy, trifluoromethyl, or nitro, and R.sup.3 is hydrogen or an alkyl, or a pharmaceutically acceptable salt thereof, which have excellent anti-allergic activities and are useful, particularly for the prophylaxis and treatment of allergic asthma, and processes for the preparation thereof, and anti-allergic agent containing said compounds as an active ingredient.
REFERENCES:
patent: 3883653 (1975-05-01), Barth
patent: 3917835 (1975-12-01), Barth
patent: 3957784 (1976-05-01), Barth
patent: 3968213 (1976-07-01), Barth
patent: 4031093 (1977-06-01), Juby
Juby, et al., Journal of Medicinal Chemistry, 22, 1979, pp. 263-269.
Chemical Abstracts, 54, 11038e (1960) Shirakawa and Zasshi.
Kataoka Mikiko
Kimura Isami
Ozeki Khoji
Sato Makoto
Sawada Masahiro
Gerstl Robert
Morishita Pharmaceutical Co. Ltd.
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