2-Aminothiazolines and a process for preparation thereof

Details 2-Aminothiazolines and a process for preparation thereof 2-Aminothiazolines and a process for preparation thereof

1974-08-06

1977-04-19

Daus, Donald G.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260240R, 424270, C07D27742

Patent

active

040187861

ABSTRACT:
Amino-2 thiazoles of the formulae ##STR1## and ##STR2## wherein R.sub.1 and R.sub.2 are each selected from hydrogen, lower alkenyl radicals, lower alkyl radicals, lower cycloalkyl radicals, phenyl radical, lower cycloalkylphenyl radicals, lower phenylalkyl radicals, lower halogenoalkenyl radicals, lower halogenoalkyl radicals, lower halogenocycloalkyl radicals, halogenophenyl radicals, lower halogenoalkyl radicals, and the same radicals substituted by at least a hydroxy, R.sub.3 and R.sub.4 are each selected from hydrogen, lower alkyl and lower cycloalkyl, one at least of R.sub.1 and R.sub.2 being cyclic, and their salts, have valuable hypocholesterolemic activity.

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