2-aminoquinolinecarboxamides: neurokinin receptor ligands

Details 2-aminoquinolinecarboxamides: neurokinin receptor ligands 2-aminoquinolinecarboxamides: neurokinin receptor ligands

2006-05-09

2006-05-09

Davis, Zinna Northington (Department: 1625)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

C546S148000, C546S149000, C546S168000, C546S169000, C544S363000, C514S233500, C514S253060, C514S299000, C514S307000, C514S313000, C514S314000, C206S828000

Reexamination Certificate

active

07041664

ABSTRACT:
Disclosed are compounds of the formula:or pharmaceutically acceptable salts or pharmaceutically acceptable solvates thereof,wherein R1, R2, R3, X, Q1and Q2are defined herein,which compounds are ligands for neurokinin receptors, in particular NK-3 receptors, and are therefor useful in the treatment of a wide range of diseases or disorders including, but not limited to depression, anxiety, psychosis, obesity, pain, Parkinson's disease, Alzheimer's disease, neurodegenerative diseases, movement disorders, respiratory diseases, inflammatory diseases, neuropathy, immune disorders, migraine, biliary disfunction, and dermatitis.

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