Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...
Patent
1978-07-14
1980-01-01
Rotman, Alan L.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Bacterium or component thereof or substance produced by said...
546 70, A61K 31445, C07D47104
Patent
active
041816579
ABSTRACT:
Novel compounds having the structural formula ##STR1## wherein R.sub.1 is hydrogen, i-propyl, phenyl or a substituted phenyl having the structure ##STR2## wherein R.sub.2 is halogen, methoxy, lower alkyl, nitro, trifluoromethyl, acetamido, or sulfonamido and their acid addition salts, are useful for treatment of cardiovascular disorders such as cardiac arrhythmia, hypertension, and angina pectoris. Methods for preparation and use of these compounds are described.
REFERENCES:
patent: 3962258 (1976-06-01), Archibald et al.
Schellenberg, K., J. Org. Chem., 28, 3259-3261 (1963).
Havera Herbert J.
Johnson Richard D.
Vidrio Horacio
Miles Laboratories Inc.
Rotman Alan L.
Schwartz Richard A.
Winchell Richard W.
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