2-aminomethylalkynylalkyl-1,3-dithiane derivatives

Details 2-aminomethylalkynylalkyl-1,3-dithiane derivatives 2-aminomethylalkynylalkyl-1,3-dithiane derivatives

1988-05-17

1989-10-31

Lee, Mary C.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Silicon containing doai

5142278, 5142315, 514252, 514326, 514422, 514436, 544 60, 544 69, 544145, 544229, 544374, 546 14, 546207, 548406, 548527, 549 4, 549 22, A61K 31385, A61K 31535, C07D40512, C07D33908

Patent

active

048777790

ABSTRACT:
Novel compounds and their salts are disclosed having the Formulas: ##STR1## wherein: R.sub.1 is hydrogen, phenyl, 9H-fluoren-9-yl, 10,11-dihydro-5H-dibenzo [a,d]cyclohepten-5-yl, 5H-dibenzo[a,d]cyclohepten-5-yl, 1,2,3,4-tetrahydro-1-naphthyl, 9H-xanthen-9-yl, 9H-thioxanthen-9-yl, 2-chloro-9H-thioxanthen-9-yl, 4H-chromanyl, diphenylmethyl, phenylcycloalkylmethyl wherein the bridgehead methylene may optionally be substituted with a hydroxy group and any of the phenyl or benzo-fused rings may be substituted with one or more R.sub.5 groups wherein R.sub.5 is selected from halogen, trifluoromethyl, lower alkyl, hydroxy or lower alkoxy groups; and

REFERENCES:
patent: 3086021 (1963-04-01), Biel

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