2-Aminomethyl phenol derivative and process for preparing thereo

Details 2-Aminomethyl phenol derivative and process for preparing thereo 2-Aminomethyl phenol derivative and process for preparing thereo

1978-12-28

1981-03-03

Lone, Werren B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

424330, 568707, C07C 8720, C07C 9130, A61K 2700

Patent

active

042540569

ABSTRACT:
A 2-aminomethyl phenol derivative of the formula (I): ##STR1## wherein X is a halogen atom; R.sup.1, R.sup.2, R.sup.3 and R.sup.4 which may be the same or different are each a hydrogen atom or a straight or branched chain alkyl group having 1 to 4 carbon atoms; n is 2, 3, 4 or 5 and a pharmaceutically acceptable acid addition salt thereof are disclosed. Also disclosed is a process for preparing such derivative or a pharmaceutically acceptable acid addition salt thereof.

REFERENCES:
patent: 3072716 (1963-08-01), Huebner
patent: 3504031 (1970-03-01), Berdahl et al.
patent: 3642785 (1972-02-01), Shen et al.
patent: 3794734 (1974-02-01), Cragee et al.
patent: 3830854 (1974-08-01), Degginger
patent: 3845063 (1974-10-01), Balls
patent: 4076843 (1978-02-01), Hauck et al.
patent: 4080380 (1978-03-01), Zenitz
Chemistry Letters, No. 1, 59-62, 1974, Claude Mareau et al.
Chemische Berichte, 93, 1774-1781, 1960, Horner et al.
Travaux de la Societe de Pharmacie de Montpellier, 24 No. 89-94, 1964, R. Granger et al.

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