Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-08-01
2006-08-01
Coleman, Brenda (Department: 1624)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C546S086000, C546S087000
Reexamination Certificate
active
07084154
ABSTRACT:
A chemical genus of 2-(aminomethyl)arylamides, which are useful as analgesics, is disclosed. The genus is represented by the formula I:A representative example is:
REFERENCES:
patent: 2328720 (1999-04-01), None
patent: WO/2001/054694 (2001-08-01), None
Isaac, Methvin et al., “5,5-Diaryl-2-amino-4-pentenoates as Novel, Potent, and Selective Glycine Transporter Type-2 Reuptake Inhibitors” Bioorganic and Medicinal Chemistry Letters, vol. 11, 2001, pp. 1371-1373.
Caulfield Wilson L. et al., “The First Potent and Selective Inhibitors of the Glycine Transporter Type 2”, Journal of Medicinal Chemistry, American Chemical Society, Washington D.C., vol. 44, No. 17, Aug. 16, 2001, pp. 2679-2682.
Ho, Koc-Kan et al., “2-(Aminomethyl)-benzamide-based glycine transporter type-2 inhibitors”, Bioorganic and Medicinal Chemistry Letters, vol. 14, 2004, pp. 545-548.
Appell Kenneth C.
Baldwin John J.
Bohnstedt Adolph C.
Guo Tao
Ho Koc-Kan
Coleman Brenda
Hansen Philip E.
Heslin Rothenberg Farley & & Mesiti P.C.
Pharmacopeia Drug Disclovery, Inc.
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