2-aminomethyl-6-sulfamoylphenol derivatives, a process for their

Details 2-aminomethyl-6-sulfamoylphenol derivatives, a process for their 2-aminomethyl-6-sulfamoylphenol derivatives, a process for their

1985-07-03

1986-08-19

Chan, Nicky

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514424, 514422, 514408, 514331, 514326, 514319, 514316, 514212, 564 86, 548523, 548542, 548578, 548950, 546191, 546206, 546208, 546232, 540596, 540597, 540602, A61K 3140, A61K 3118, C07D20700, C07C14380

Patent

active

046070303

ABSTRACT:
The invention relates to 2-aminomethylphenols of the formula I ##STR1## in which R.sup.1 and R.sup.2 represent hydrogen, alkyl, alkenyl, alkynyl, cycloalkyl or benzyl which is optionally substituted by alkyl, alkoxy or halogen, R.sup.3 and R.sup.5 denote hydrogen, halogen, alkyl or alkoxy, R.sup.4 denotes halogen, alkyl or cycloalkyl and R.sup.6 and R.sup.7 represents hydrogen or alkyl, it being possible for the radicals R.sup.1 and R.sup.2, R.sup.6 and R.sup.7 and/or two of the radicals R.sup.3, R.sup.4 and R.sup.5 to form an alkylene chain which is optionally substituted by methyl groups and which, in the case of the radicals R.sup.1, R.sup.2, R.sup.6 and R.sup.7, can also be interrupted by oxygen atoms, sulfur atoms and/or imino groups, and to physiologically acceptable salts thereof, a process for their preparation, and their use and to pharmaceutical formulations based on these compounds.

REFERENCES:
patent: 3806534 (1974-04-01), Feit
patent: 4082851 (1978-04-01), Feit et al.
Stokker et al., J. Med. Chem., 1980, 23, 1414-1427.
Patent Abstracts of Japan, vol. 3, No. 87, 1979; p. 41, C 53 8 JP A- 54 63048.

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