2-aminoindan compounds as 5HT.sub.1B antagonists

Details 2-aminoindan compounds as 5HT.sub.1B antagonists 2-aminoindan compounds as 5HT.sub.1B antagonists

1998-02-26

1999-10-19

Chang, Ceila

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

514318, 514319, 514324, 514422, 546115, 546193, 546196, 546197, 546202, 546204, 546205, 548525, 548526, 548527, A61K 31445, C07D40512

Patent

active

059689544

ABSTRACT:
New 2-aminoindan compounds of formula: ##STR1## wherein: n, Ar, R, E, X.sub.1, X.sub.2, X.sub.3, and X.sub.4 are as defined in the description, in the form of a racemic mixture and in the form of optical isomers, and physiologically-tolerable acid addition salts thereof. The products of the invention are useful as medicaments and exhibit selective binding affinity for the 5HT.sub.1B receptors.

REFERENCES:
patent: 5767116 (1998-06-01), Kerrigan et al.

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