2-[(amino-pyridinyl)amine]phenyl]aryl methanones, their thioxome

Details 2-[(amino-pyridinyl)amine]phenyl]aryl methanones, their thioxome 2-[(amino-pyridinyl)amine]phenyl]aryl methanones, their thioxome

1985-09-03

1987-05-26

Fan, Jane T.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Heterocyclic carbon compounds containing a hetero ring...

514233, 514253, 514332, 514333, 514318, 514339, 514340, 514336, 546194, 546272, 546281, 546283, 546284, 546256, 546262, 546307, 544131, 544124, 544364, 544360, C07D40102, A61K 3144

Patent

active

046686754

ABSTRACT:
Pyrido[1,4]benzodiazepines having antidepressant activity of the formula ##STR1## wherein Ar is 2, 3 and 4-pyridinyl, 2 or 3-thienyl, phenyl or a substituted phenyl; R is hydrogen, loweralkyl or an amine on the end of a hydrocarbon chain; Z is hydrogen, halogen, trifluoromethyl, loweralkyl, lower-alkoxy, hydroxy or nitro; and Y is hydrogen, loweralkyl, loweralkoxy or hydroxy; and the pharmaceutical salts are prepared from [2-[(aminopyridinyl)amino]phenyl]arylmethanones which also have antidepressant activity.

REFERENCES:
patent: 4480100 (1984-10-01), Lo et al.
Kobayashi CA 84:164876a.

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