Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal
Patent
1976-08-11
1978-07-25
Rush, Raymond V.
Chemistry of carbon compounds
Miscellaneous organic carbon compounds
C-metal
260239BC, 2603067T, 260327R, 260333, 260522R, 260553R, 260563R, 260563P, 424244, 424246, 42424856, 424251, 424270, 424273R, 544 53, 544 88, 544330, 548351, 560115, C07D26328
Patent
active
041028902
ABSTRACT:
Cyclopropylmethylamines which are substituted on the 2-position of nitrogen heterocycles so as to provide new compounds of the formula ##STR1## wherein A is oxygen, sulfur, or nitrogen; the other "R" variables in general are hydrogen, lower-alkyl, cyclopropyl, or lower-alkyl substituted cyclopropyl; and the n's are the numbers 0 to 3, inclusive, and acid addition salts thereof, are disclosed. The compounds are cardiovascular agents, which are depressive of the central nervous system. Their effects include hypnosis, analgesia, and neuro-modulation. They can be used as anti-hypertensive agents.
REFERENCES:
patent: 3598833 (1971-08-01), Hiltmann et al.
patent: 3626067 (1971-12-01), Harvey
Desnos Monique
Laubie Michel
Malen Charles
Poignant Jean-Claude
Hueschen Gordon W.
Rush Raymond V.
Science-Union et Cie, Societe Francaise de Recherche Medicale
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