Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Recombinant or stably-transformed bacterium encoding one or...
Patent
1979-01-25
1980-04-29
Friedman, Stanley J.
Drug, bio-affecting and body treating compositions
Antigen, epitope, or other immunospecific immunoeffector
Recombinant or stably-transformed bacterium encoding one or...
A61K 31195
Patent
active
042006503
ABSTRACT:
New 2-amino-cyclopent-1-ene-thiocarboxylic acid-disulfides of the general formula (I), ##STR1## wherein R is hydrogen, a C.sub.1-6 alkyl group having optionally a C.sub.1-4 alkoxy, hydroxy, carboxy and/or amino substituent, a C.sub.2-4 alkenyl group, a C.sub.3-8 cycloalkyl group or phenyl group, are prepared by oxidizing the respective 2-amino-cyclopent-1-ene-dithiocarboxylic acids of the general formula (II), ##STR2## wherein R is as defined above. The new compounds of the general formula (I) and their salts exert dopamine-.beta.-hydroxylase inhibiting effects and can be applied in the therapy.
Bartok nee Berencsy Piroska
Karpati Egon
Kiss Bela
Matolcsy Gyorgy
Palosi Eva
Friedman Stanley J.
Richter Gedeon Vegyeszeti Gyar Rt.
Ross Karl F.
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