2-amino- and 2-thio- substituted 1,3-diaminopropanes

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Nitrogen containing other than solely as a nitrogen in an...

Reexamination Certificate

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Details

C514S311000, C514S432000, C514S456000, C514S601000, C514S605000, C546S171000, C549S023000, C549S404000, C564S080000, C564S099000, C564S123000, C564S220000

Reexamination Certificate

active

07544717

ABSTRACT:
Disclosed are compounds of the formula:where variables Q, Z, X, R15, R2, R3, and Rcare defined herein. Compounds disclosed herein are inhibitors of the beta-secretase enzyme and are therefore useful in the treatment of Alzheimer's disease and other diseases characterized by deposition of A beta peptide in a mammal.

REFERENCES:
patent: 6133315 (2000-10-01), Lu et al.

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