2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, producti

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Peptide containing doai

Patent

Rate now

  [ 0.00 ] – not rated yet Voters 0   Comments 0

Details

514 16, 514 17, 514 18, 514 19, 530328, 530329, 530330, 530331, 562426, 562556, A61K 3800, C07K 500, C07K 700, C07K 1700

Patent

active

054788080

ABSTRACT:
A compound of the formula: ##STR1## wherein each of R.sup.1 and R.sup.2 is hydrogen or aliphatic acyl, A is amino which may be protected, X is an amino acid sequence consisting of 1 to 10 amino acid residues which contain at least one amino acid residue having a water-solubility enhancing group, or a salt thereof has an activity of remarkably improving hematopoietic disorder and is useful as an immuno-stimulating agent or an agent for treating thrombocytopenia.

REFERENCES:
patent: 4666886 (1987-05-01), Baschang et al.
Metzger et al., Int. J. Peptide Protein Res., "Synthesis of N.sub..alpha. -Fmoc protected derivatives of S-(2,3-dihydroxyproply)-cysteine and their application in peptide synthesis", vol. 38, No. 6, pp. 545-554 (1991).
Chem. Pharm. Bull, "Synthesis of Optically Active Lipopeptide Analogs from the Outer Membrane of Escherichia Coli" Kurimura et al., 39 (10), pp. 2590-2596 (1991).
Chem. Pharm. Bull, "Synthesis and Mitogenic Activity of Chiral Lipopeptide WS 1279 and Its Derivatives" Kurimura et al., 41 (11), pp. 1965-1970 (1993).
Chem. Pharm. Bull., "Synthesis of Biologically Active Pentapeptide Analogs of the N-Terminal Part of Lipoprotein From the Outer Membrane of Escherichia coli" Kurimura et al., 38 (4), pp. 1110-1112 (1990).
Peptide Chemistry 1990: Y. Shimonishi (Ed.), Protein Research Foundation, Osaka, Japan (1990), "Synthesis and Mitogenic Activity of Lipopeptide and Its Analogs" Kurimura et al., pp. 37-42.
Peptide Chemistry 1991: A. Suzuki (Ed.) Protein Research Foundation, Osaka, Japan (1991), "Stereospecific Synthesis and Mitogenic Activity of Lipopeptide WS 1279 and Its Derivatives" Kurimura et al., pp. 361-366.
Int. J. Peptide Protein Res., "Synthesis of Novel Immunologically Active Tripalmitoyl-S-Glycerylcysteinyl Lipopeptides as Useful Intermediates for Immunogen Preparations" Metzger et al., 37, 1991, pp. 46-57.

LandOfFree

Say what you really think

Search LandOfFree.com for the USA inventors and patents. Rate them and share your experience with other people.

Rating

2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, producti does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, producti, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-amino-6,7-dihydroxy-4-thiaheptanoic acid derivatives, producti will most certainly appreciate the feedback.

Rate now

     

Profile ID: LFUS-PAI-O-1369229

  Search
All data on this website is collected from public sources. Our data reflects the most accurate information available at the time of publication.