2-Amino-5-(trifluoromethyl phenylalkyl)-1,3,4-thiadiazoles

Details 2-Amino-5-(trifluoromethyl phenylalkyl)-1,3,4-thiadiazoles 2-Amino-5-(trifluoromethyl phenylalkyl)-1,3,4-thiadiazoles

1974-11-29

1976-06-22

Gallagher, R.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260552SC, 424270, C07D28512

Patent

active

039651100

ABSTRACT:
2-amino-5-(substituted or unsubstituted phenylalkyl)-1,3,4-thiadiazoles, e.g., 2-amino-5-(3-trifluoromethylbenzyl)-1,3,4-thiadiazole, prepared, e.g., by ring closure, of corresponding 1-(substituted or unsubstituted phenylalkanoyl)-thio-semicarbazide in a strong acid medium. The compounds are useful as minor tranquilizers and sleep inducers.

REFERENCES:
elderfield (ed.), Heterocyclic Compounds, vol. 7, Wiley, N.Y., 1961, pp. 587-595.

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