2-Amino-5-spiro substituted oxazoline-4-one compounds

Details 2-Amino-5-spiro substituted oxazoline-4-one compounds 2-Amino-5-spiro substituted oxazoline-4-one compounds

1973-02-20

1976-01-06

Winters, Sherman D.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07D21118

Patent

active

039311988

ABSTRACT:
A novel series of 2-amino-5-spiro substituted oxazolin-4-ones and intermediates for making said compounds. These compounds are prepared by first converting the appropriately substituted cycloketone to the corresponding cyclocyanohydrin; converting this compounds to the corresponding hydroxy acid; esterifying the hydroxy acid, and finally cyclizing the hydroester to form the 2-amino-5-spiro substituted oxazolin-4-one. These compounds exhibit central nervous system activity and are active as either stimulants or depressants, and some are useful as performance enhancers.

REFERENCES:
J. Med. Chem., 12:919-922, (1969), Harnden et al.
J. Med. Chem., 13:305-308, (1970), Harnden et al.

Affiliated with

Also associated with

Rating

2-Amino-5-spiro substituted oxazoline-4-one compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with 2-Amino-5-spiro substituted oxazoline-4-one compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and 2-Amino-5-spiro substituted oxazoline-4-one compounds will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-2349013