2-amino-4-phenylquinazoline derivatives and the use thereof...

Details 2-amino-4-phenylquinazoline derivatives and the use thereof... 2-amino-4-phenylquinazoline derivatives and the use thereof...

2011-05-24

2011-05-24

Wilson, James O (Department: 1624)

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

C544S292000, C544S359000, C546S268100, C548S250000, C548S335100, C548S362500, C548S503000

Reexamination Certificate

active

07947696

ABSTRACT:
Novel phenylquinazoline derivatives of the formula (I), in which R1, R2, R3, R4and R5have the meanings indicated in Claim1, are HSP90 inhibitors and can be used for the preparation of a medicament for the treatment of diseases in which the inhibition, regulation and/or modulation of HSP90 plays a role.

REFERENCES:
patent: 5646154 (1997-07-01), Irie et al.
patent: 6800644 (2004-10-01), Miyazaki et al.
patent: 2005/0096327 (2005-05-01), Caprathe et al.
patent: 0 664 128 (1995-07-01), None
patent: 664 128 (1995-07-01), None
patent: WO 02/24682 (2002-03-01), None
patent: WO-02 102782 (2002-12-01), None
patent: WO 2005/021552 (2005-03-01), None
patent: WO-2005 021552 (2005-03-01), None
Jordan, V. C. Nature Reviews: Drug Discovery, 2, 2003, p. 205.
Dörwald, F. Zaragoza. Side Reactions in Organic Synthesis: A Guide to Successful Synthesis Design, Weinheim: Wiley-VCH Verlag GmbH & Co. KGaA, 2005, Preface.
Vippagunta, et al. Advanced Drug Delivery Reviews, 48, 2001, p. 18.
Office Action issued on Mar. 18, 2010 for Russian Patent Application No. 2007 146 388.
German Translation of Office Action issued on Mar. 18, 2010 for Russian Patent Application No. 2007 146 388.

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