2-amino-4-oxo-tricyclicpyrimidines having antiviral activities a

Details 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities a 2-amino-4-oxo-tricyclicpyrimidines having antiviral activities a

1983-10-13

1986-11-25

Daus, Donald G.

Organic compounds -- part of the class 532-570 series

Organic compounds

Four or more ring nitrogens in the bicyclo ring system

514268, 544287, 544253, 424 28, C07D48700, A61K 31505

Patent

active

046250263

ABSTRACT:
In one aspect, compounds having antiviral activity and having the general formula: ##STR1## wherein each R.sup.2, independently, is H or lower (fewer than 6 carbon atoms) alkyl; each R.sup.3, independently, is H or lower alkyl R.sup.0 is H or lower alkyl, R.sup.1 is H or lower alkyl; 1.ltoreq.n.ltoreq.11; n-2.ltoreq.m.ltoreq.2n; 0.ltoreq.p.ltoreq.3; z is 0 or 1; and p.ltoreq.q.ltoreq.2p; each n, m, p and q being selected so that the sp.sup.3 valence shell of each carbon atom in each ring is filled; or a pharmaceutically acceptable salt thereof.

REFERENCES:
patent: 3057467 (1962-10-01), Williams
patent: 3185691 (1965-05-01), Pribyl
patent: 3257400 (1966-06-01), Wagner
patent: 3398826 (1968-08-01), Clancy
patent: 3609152 (1971-10-01), Hess et al.
patent: 3786615 (1974-01-01), Bauer
patent: 3941787 (1976-03-01), Salmond

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