2-amino-4,5-dihydro-1H-imidazole-1-carboxanilides

Details 2-amino-4,5-dihydro-1H-imidazole-1-carboxanilides 2-amino-4,5-dihydro-1H-imidazole-1-carboxanilides

1985-01-14

1986-10-21

Fan, Jane T.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23346

Patent

active

046186824

ABSTRACT:
Novel 2-amino-4,5-dihydro-1H-imidazole-1-carboxanilides, which are made by reacting 2-amino-4,5-dihydroimidazole with an aryl isocyanate, are made stable to rearrangement when converted to acid addition salt form, and are useful either as antihypertensive agents and/or antisecretary agents, as well as being intermediates to prepare known pharmacologically active N-aryl-N'-(4,5-dihydro-1H-imidazol-2-yl)ureas.

REFERENCES:
patent: 4229462 (1980-10-01), Rasmussen
patent: 4239768 (1980-12-01), Rasmussen

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