Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2006-03-28
2006-03-28
Lambkin, Deborah C. (Department: 1626)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C549S057000
Reexamination Certificate
active
07019027
ABSTRACT:
The present invention relates to a compound of formula (I):wherein:R3is selected from the group consisting of 1-napthyl, 2-napthyl and cycloalkylphenyl; andR4and R5taken together form a ring having from 5 to 10 carbon atoms.Additionally, the invention provides a therapeutic method for preventing or treating a pathological condition or symptom in a mammal subject, such as a human, wherein increased angiogenesis is desired, comprising administering to a mammal in need of such therapy an effective amount of the aforementioned thiophene selective adenosine A1allosteric enhancer.
REFERENCES:
patent: 6177444 (2001-01-01), Baraldi
Tinney et al , “Synthesis and Pharmaceutical Evaluation of . . . Thieno . . . Diazepines”, CA81:145630, 1974.
Linden Joel M.
Ollson Ray A.
Scammells Peter J.
Calkins Charles W.
Kilpatrick & Stockton LLP
Lambkin Deborah C.
Wimbish J. Clinton
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