2-Amino-3-acylamino-6-benzylamino-pyridine-derivative having ant

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...

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546308, A61K 3144, C07D21374

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active

045542813

ABSTRACT:
Compounds of the formula ##STR1## where R is a C.sub.1 -C.sub.4 alkyl group, a C.sub.1 -C.sub.4 alkoxy group, a phenoxy group or a phenyl-C.sub.1 -C.sub.2 -alkoxy group, R.sub.1 is hydrogen or a C.sub.1 -C.sub.4 -alkyl group and R.sub.5 is hydrogen or a C.sub.1 -C.sub.4 -alkyl group and the groups R.sub.2, R.sub.3, and R.sub.4 are the same or different and are hydrogen, halogen atoms, C.sub.1 -C.sub.4 alkyl groups, C.sub.1 -C.sub.4 -alkylcarbonyl group, the aminosulfonyl group, the trifluoromethyl group and their acid addition salts are effective as antiepileptics.

REFERENCES:
Richens, A., "Drug Treatment of Epilepsy", Henry Kimpton Publishers, London, (1976) pp. 53-60.
Urca, G. et al, "Morphine and Enkephalin", Chemical Abstracts, 87: 95940q (1977).
Sewell, R. D. E., "Proconvulsant Action of Aspirin", Chemical Abstracts, 99: 151817s (1983).

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