Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Phosphorus containing other than solely as part of an...
Patent
1997-08-14
1999-09-14
Kight, John
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Phosphorus containing other than solely as part of an...
514119, 514255, 514357, 514372, 514403, 514477, 514438, 514459, 514471, 544421, 546210, 546246, 546247, 546334, 548214, 548373, 548516, 549 75, 549426, 549498, 560 11, 560172, 564336, 564340, 564342, 564346, 564374, 564383, 564454, 564123, A01N 5700, A01N 4360, C07P40100, C07P21100
Patent
active
059523166
ABSTRACT:
2-Amino-1,3-propanediol compounds of the formula (I) ##STR1## wherein R is an optionally substituted straight- or branched carbon chain, an optionally substituted aryl, an optionally substituted cycloalkyl or the like, and R.sup.2, R.sup.3, R.sup.4 and R.sup.5 are the same or different and each is a hydrogen, an alkyl, an aralkyl, an acyl or an alkoxycarbonyl, pharmaceutically acceptable salts thereof and immunosuppressants comprising these compounds as active ingredients.
The 2-amino-1,3-propanediol compounds of the present invention show immunosuppressive action and are useful for suppressing rejection in organ or bone marrow tranplantation, prevention and treatment of autoimmune diseases or as reagents for use in medicinal and pharmaceutical fields.
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Adachi Kunitomo
Chiba Kenji
Fujita Tetsuro
Mishina Tadashi
Sasaki Shigeo
Covington Raymond
Kight John
Taito Co., Ltd.
Yoshitomi Pharmaceutical Industries Ltd.
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