2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the

Details 2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the 2-amino-1,2,3,4-tetrahydronaphthalene derivatives active on the

1993-03-17

1995-04-18

Dees, Jose G.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Ester doai

514114, 514651, 560134, 560139, 560190, 562 11, 564354, A61K 31215

Patent

active

054079560

ABSTRACT:
Derivatives of 2-amino-1,2,3,4-tetrahydronaphthalene and their use in therapeutic field are described.
The compounds are particularly useful in the treatment of arterial hypertension, cardiac decompensation and renal failure, in the treatment of peripheral arteriopathies and in cerebrovascular insufficiency.

REFERENCES:
The Merck Index, An Encyclopedia of Chemicals, Drugs, and Biologicals, 11th Ed., (1989) p. 583.
Haralambos E. Katerinopoulos, et al, "Correlates in Pharmacostructures", Structure-Activity Relationships for Dopamine Analogs: A Review, vol. 12 No. 3 (1987) pp. 223-248.
Andrew Fitton et al, "Drug Evaluation" Dopexamine hydrochloride: A Review of its Pharmacodynamic and Pharmacokinetic Properties and Therapeutic Potential in Acute Cardiac Insufficiency, Drugs 39, (2) (1990) pp. 308-330.

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