2.alpha.-fluorovitamin D.sub.3

Details 2.alpha.-fluorovitamin D.sub.3 2.alpha.-fluorovitamin D.sub.3

1985-03-20

1986-06-10

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

C07J 900

Patent

active

045941920

ABSTRACT:
The invention provides new derivatives of vitamin D.sub.3, 2.alpha.-fluorovitamin D.sub.3 and the acylates thereof.
The compounds are characterized by vitamin D-like activity in their ability to increase intestinal calcium transport and serum calcium indicating their ready application as substitutes for vitamin D.

REFERENCES:
patent: 4254045 (1981-03-01), DeLuca et al.
patent: 4307025 (1981-12-01), DeLuca et al.
Journal of Labelled Compounds Radio-Pharm. (1984) England, vol. 21, No. 8, pp. 759-766, as Abstracted in Chem. Abstracts (1985) vol. 102, par 95,901f.

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