2.alpha., 3.beta., 4a.beta., 8a.alpha.-Decahydro-3-(4-phenyl-1-p

Details 2.alpha., 3.beta., 4a.beta., 8a.alpha.-Decahydro-3-(4-phenyl-1-p 2.alpha., 3.beta., 4a.beta., 8a.alpha.-Decahydro-3-(4-phenyl-1-p

1984-07-31

1985-11-12

Schwartz, Richard A.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D21114

Patent

active

045529655

ABSTRACT:
A compound denominated (2.alpha., 3.beta., 4a.beta., 8a.alpha.)-decahydro-3-(4-phenyl-1-piperidinyl)-2-naphthalenol(DPPN) having the following chemical structure: ##STR1## DPPN is more effective than other known compounds in blocking presynaptic release of acetylcholine at cholinergic synapses.

REFERENCES:
patent: 2352020 (1944-06-01), Scheving et al.
March, J., Advanced Organic Chemistry, McGraw Hill, New York, 1968, p. 334.
Marshall, I. G., Br. J. Pharmac., vol. 38, pp. 503-516 (1970).

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