2-Alkyl-4-amino-5-aminomethylpyrimidines

Details 2-Alkyl-4-amino-5-aminomethylpyrimidines 2-Alkyl-4-amino-5-aminomethylpyrimidines

1987-07-14

1988-12-27

Ford, John M.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

544329, C07D23942

Patent

active

047941820

ABSTRACT:
A novel 2-lower alkyl-4-amino-5-substituted iminopyrimidine compound represented by the formula: ##STR1## wherein R is a lower alkyl, and Y is hydroxyl or amino which may be protected or a salt thereof is obtainable by allowing a formylpyrimidine compound represented by the formula: ##STR2## wherein R is a lower alkyl to react with a compound represented by the formula H.sub.2 N--Y, wherein Y is hydroxyl or amino which may be protected, or a salts thereof. The iminopyrimidine compound gives the known pyrimidine compound represented by the formula: ##STR3## wherein R is as defined above in high yield. Therefor, the process is very useful as an industrial production method.

REFERENCES:
patent: 4536577 (1985-08-01), Yoshida et al.
patent: 4539403 (1985-09-01), Fujii et al.
Kozo et al., Chemical Abstracts, vol. 99, entry 175794h (1983).
Ube Industries., Chemical Abstracts, vol. 101, entry 90962w (1984).
Ube Industries., Chemical Abstracts, vol. 102, entry 149287f (1985).

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