Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1989-01-23
1991-09-10
Ivy, C. Warren
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D21726
Patent
active
050475452
ABSTRACT:
2-Methoxycarbonyl-4-(4-pyridyl)cyclohexanone of the present invention is an important intermediate for preparing isoquinoline derivatives which are useful as medicines, particularly as heart medicines.
REFERENCES:
Windholz et al, The Merck Index, 1976, p. ONR-23.
Lochte et al., JACS, Sep. 20, 1953, pp. 4477-4481.
Modern Synthetic Reactions, "The Organic Chemistry Monograph Series", H. House, 2nd Edition, pp. 740-743 (1972).
Isoquinolines Part 1, G. Grethe, pp. 252-253 (1981).
Chemical Abstracts, vol. 76, No. 23, p. 450 (1972) Abstract No. 140,475c.
Tetrahedron, The Knoevenagel Reaction of Malononitrile with Some Cyclic . . . , J. L. van Der Baan & F. Bickelhaupt, vol. 30, pp. 2447-2453 (1974).
Fukazawa Nobuyuki
Yamashita Hiroyuki
Ivy C. Warren
Mitsui Toatsu Chemicals Inc.
Northington-Davis Zinna
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