Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Having -c- – wherein x is chalcogen – bonded directly to...
Reexamination Certificate
2003-01-15
2009-12-29
Chang, Celia (Department: 1625)
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Having -c-, wherein x is chalcogen, bonded directly to...
C514S235500, C514S254020, C514S316000, C544S360000, C544S369000, C546S193000, C546S212000
Reexamination Certificate
active
07638536
ABSTRACT:
A 2-acylaminothiazole derivative or a pharmaceutically acceptable salt thereof having an excellent effect of proliferating human c-mpl-Ba/F3 cells and an activity of increasing platelets based on the effect of promoting the formation of megakaryocytic colonies. A compound or a pharmaceutically acceptable salt thereof useful in treating thrombocytopenia.
REFERENCES:
patent: 5189049 (1993-02-01), Frehel et al.
patent: 5256675 (1993-10-01), Matsuo et al.
patent: 5314889 (1994-05-01), Boigegrain et al.
patent: 5330998 (1994-07-01), Clark et al.
patent: 5369107 (1994-11-01), Matsuo et al.
patent: 5380736 (1995-01-01), Boigegrain et al.
patent: 5384331 (1995-01-01), Kogan et al.
patent: 5583131 (1996-12-01), Bridger et al.
patent: 5728709 (1998-03-01), Ikuina et al.
patent: 5932546 (1999-08-01), Barrett et al.
patent: 5963666 (1999-10-01), Fujisaki et al.
patent: 6040335 (2000-03-01), Saitoh et al.
patent: 6083913 (2000-07-01), Dower et al.
patent: 6498155 (2002-12-01), Luengo et al.
patent: 6962935 (2005-11-01), Pruitt et al.
patent: 7384967 (2008-06-01), Polisetti et al.
patent: 2003/0195231 (2003-10-01), Takemoto et al.
patent: 2004/0053982 (2004-03-01), Press et al.
patent: 2004/0063946 (2004-04-01), Ohkawa et al.
patent: 2004/0073029 (2004-04-01), Pruitt et al.
patent: 2004/0077697 (2004-04-01), Koshio et al.
patent: 2004/0122235 (2004-06-01), Polisetti et al.
patent: 2004/0235834 (2004-11-01), Farmer et al.
patent: 2005/0153977 (2005-07-01), Sugasawa et al.
patent: 2006/0194844 (2006-08-01), Sugasawa et al.
patent: 2007/0043087 (2007-02-01), Takayama et al.
patent: 0412404 (1996-01-01), None
patent: 0518731 (1998-08-01), None
patent: 1 207 155 (2002-05-01), None
patent: 1 253 142 (2002-10-01), None
patent: 3-68567 (1991-03-01), None
patent: 3173876 (1991-07-01), None
patent: 3199451 (1991-08-01), None
patent: AH-05-155871 (1993-06-01), None
patent: 11-152276 (1999-06-01), None
patent: WO 00/17175 (2000-03-01), None
patent: WO 00/35446 (2000-06-01), None
patent: 0107423 (2001-02-01), None
patent: WO 01/53267 (2001-07-01), None
patent: 0242298 (2002-05-01), None
patent: WO-02/053160 (2002-07-01), None
patent: 02062775 (2002-08-01), None
patent: 02062792 (2002-08-01), None
patent: WO-03/075921 (2003-09-01), None
patent: WO-03/084544 (2003-10-01), None
patent: WO 03/103657 (2003-12-01), None
patent: WO-2004/002481 (2004-01-01), None
patent: WO 2004/029049 (2004-04-01), None
patent: WO-2004/071447 (2004-08-01), None
patent: WO 2005/007651 (2005-01-01), None
patent: WO 2005/014561 (2005-02-01), None
Cook et al. “Azole series . . . ” CA 43:6451 (1949).
Muto et al. “Preparation of . . . ” CA 140:42203 (2003).
Muto et al. “Preparation of phenol . . . ” CA 140:422216 (2003).
Takayama et al. “preparation of thiazole . . . ” CA 142:240425 (2005).
Nakajima et al. “Synthesis of thaizole . . . ” CA 143:133362 (2005).
Uesaka et al. “Preparation of thiazole . . . ” CA 146:229330 (2007).
Sugasawa et al. “preparation of maleic acid . . . ” CA 140:321382 (2004).
K. Hirai et al., “Syntheses of 2-Disubstituted-amino-4-arylthiazol-5-ylalkanoic Acids”, Chem. Pharm. Bull., vol. 25, pp. 2292-2299, (1977).
Mutschler et al., Drug Actions: Basic Principles and Therapeutic Aspects, 1995, CRC Press, pp. 6-8.
Braga, Dario et al., “Making crystals from crystals: a green route to crystal engineering and polymorphism,”Chem. Commun., vol. 29:3635-3645 (2005).
Morissette, Sherry et al., “High-throughput crystallization: polymorphs, salts, co-crystals and solvates of pharmaceutical solids,”Advanced Drug Delivery Reviews, vol. 56:275-300 (2004).
Vippagunta, Sudha et al., “Crystalline solids,”Advanced Drug Delivery Reviews, vol. 48:3-26 (2001) (Abstract).
Kimura, Tatsuya, et al., “A non-peptide compound which can mimic the effect of thrombopoietin via e-mpl”, FEBS Letters. 428, 1998, 250-254.
International Search Report for WO 2005/007651, corresponding to U.S. Appl. No. 10/564,520, (2005).
International Preliminary Report on Patentability from International Application No. PCT/IB2006/003142 (corresponding to U.S. Appl. No. 11/593,758), (2007).
Kuter, et al., Recombinant Human Thrombopoietin: Basic Biology and Evaluation of Clinical Studies, Blood 2002, vol. 100, No. 10.
Vadhan-Raj, et al., “Recom. Hum. Thrombopoietin Attenuates Carboplatin-Indcd. Svre. Thrombocytopenia”, Annals of Internal Medicine 2002, vol. 132, No. 5, pp. 364-368.
Vadhan-Raj, et al., “Import. of Predosing of Recomb. Hum. Thrombopoietin to Rdce. Chemotherapy-Indcd. Erly.”, Journal of Clinical Oncology 2003, vol. 21, No. 16, pp. 3158-3167.
Mutschler et al., “Drug Actions: Basic Principles and Therapeutic Aspects”, 1005, CRC Press, pp. 6-8, (1995).
Hirayama Fukushi
Koga Yuji
Nagata Hiroshi
Obitsu Kazuyoshi
Sugasawa Keizo
Astellas Pharma Inc.
Chang Celia
Davidson Davidson & Kappel LLC
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