2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t

Drug – bio-affecting and body treating compositions – Antigen – epitope – or other immunospecific immunoeffector – Bacterium or component thereof or substance produced by said...

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544 58, 544 32, 544102, 544115, 544182, 544215, 544235, 544234, 544237, 544238, 544252, 544256, 544257, 544277, 544283, 544295, 544344, 544347, 544357, A61K 31495, C07D47104

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041138678

ABSTRACT:
2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline with an acid or a reactive functional derivative thereof.

REFERENCES:
patent: 3684813 (1972-08-01), Seubert et al.
patent: 4001411 (1977-01-01), Archer et al.

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