2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t

Details 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t

1978-12-18

1980-04-01

Tovar, Jose

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

424250, C07D47104, H61K 31495

Patent

active

041962915

ABSTRACT:
2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline with an acid or a reactive functional derivative thereof. This is a division, or application Ser. No. 742,133, filed on Nov. 15, 1976, which in turn is a divisional of Ser. No. 533,467, filed on Dec. 16, 1974, now U.S. Pat. No. 4,001,411.

REFERENCES:
patent: 4001411 (1977-01-01), Seubert et al.
patent: 4049659 (1977-09-01), Pohlke
patent: 4051243 (1977-09-01), Seubert et al.
patent: 4141978 (1979-02-01), Seubert et al.

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