2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t

Details 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t 2-Acyl-4-oxo-pyrazino-isoquinoline derivatives and process for t

1974-12-16

1977-01-04

Gallagher, R.

Drug, bio-affecting and body treating compositions

Antigen, epitope, or other immunospecific immunoeffector

Bacterium or component thereof or substance produced by said...

260250BC, 260268TR, 424200, 424232, C07D24136

Patent

active

040014118

ABSTRACT:
2-Acyl-4-oxo-hexahydro-4H-pyrazino[2,1-a]isoquinoline derivatives of the formula ##STR1## wherein COR is the acyl radical of an up to 26 carbon atom acid and their physiologically acceptable acid addition and quaternary ammonium salts, are anthelmintics and can be produced by reacting 4-oxo-1,2,3,6,7,11b-hexahydro-4H-pyrazino[2,1-a]isoquinoline with an acid or a reactive functional derivative thereof.

REFERENCES:
burger, Medicinal Chemistry 3rd Ed., Part I, p. 638.
Burger, Medicinal Chemistry 3rd Ed., Part II, p. 1588.

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