2-acetylpyridine thiosemicarbazones as antiviral agents

Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...

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514210, 514218, 514227, 514247, 514250, 514315, 514344, 514408, 514512, 514717, 514731, 514732, 514737, 514934, A61K 3133, A61K 31395, A61K 3155, A61K 31535

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active

045967989

ABSTRACT:
This invention relates to the use of various 2-acetylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom in the treatment of viral infections. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.

REFERENCES:
patent: 4317776 (1982-03-01), Klayman et al.
Brockman et al. I, Observation on the AntiLeukemic Activity of Pyridine 2rboxaldehyde thiosemicarbazone Can. Res., 16:167-170, 1956.
Brockman et al. II, Hetero. Thiosemicarbazones: Correlation Between Structure . . . DNA viruses, Proc. Soc. Exp. Bio. Med. 133, 609-614, 1970.

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