2-acetylpyridine 5-[(2-chloroanilino)thiocarbonyl]thiocarbonohyd

Details 2-acetylpyridine 5-[(2-chloroanilino)thiocarbonyl]thiocarbonohyd 2-acetylpyridine 5-[(2-chloroanilino)thiocarbonyl]thiocarbonohyd

1989-06-26

1991-06-04

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

546331, A61K 3144, C07D21302

Patent

active

050214373

ABSTRACT:
The present invention relates to a novel ribonucleotide reductase inhibitor and new combinations comprising an antiviral compound, such as acyclovir, and a thiocarbonohydrazone ribonucleotide reductase inhibitor for the chemotherapeutic treatment of virus infections, especially viruses of the herpes group.

REFERENCES:
patent: 4199574 (1980-04-01), Schaeffer
patent: 4323573 (1982-04-01), Schaeffer
patent: 4606917 (1986-08-01), Eppstein
patent: 4609662 (1986-09-01), Kuenitsky
patent: 4777166 (1988-10-01), Smith et al.
Chemical Abstracts, vol. 103, No. 9, Abstract No. 76243x, Sep. 2, 1985, Averett et al.
Shipman, Jr., et al., Antiviral Research, 6 (1986), 197-222.

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