Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1984-12-07
1988-04-19
Jiles, Henry R.
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D21353
Patent
active
047390697
ABSTRACT:
This invention relates to various 2-acetyl- and 2-propionylpyridine thiosemicarbazones which are substituted on the 4-nitrogen atom. These compounds are useful in the treatment of gonorrhea and, in addition, many are useful either in the treatment of malaria or bacterial infection. Also disclosed are several synthetic procedures used to prepare the thiosemicarbazones.
REFERENCES:
patent: 2723270 (1955-11-01), Scudi
Chemical Abstracts 69:59112r.
Klayman, D. L., "2-Acetylpyridine Thiosemicarbazones 1", J. Med. Chem., v 22, No. 7, (1979), pp. 855-862.
Klayman, D. L., "2-Acetylpyridine Thiosemicarbazones 2", J. Med. Chem., vol. 22, No. 11 (1979), pp. 1367-1373.
Collins, F. M. et al., J. General Microbiology, (1982), 128, pp. 1349-1356.
Bartosevich Joseph F.
Griffin T. Scott
Klayman Daniel L.
Mason Carl J.
Scovill John P.
Bellamy Werten F. W.
Bjorkman Dale A.
Gapcynski William G.
Jiles Henry R.
The United States of America as represented by the Secretary of
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