2-acetoxymethyl-4-halo-butyl-1-yl acetates

Details 2-acetoxymethyl-4-halo-butyl-1-yl acetates 2-acetoxymethyl-4-halo-butyl-1-yl acetates

1997-06-30

1999-03-23

Geist, Gary

Organic compounds -- part of the class 532-570 series

Organic compounds

Carboxylic acid esters

C07C 6702

Patent

active

058862153

ABSTRACT:
The present invention provides a process for the synthesis of penciclovir and famciclovir by 9-substituting 2-amino-6-chloropurine (ACP) with an appropriate side chain precursor, followed by conversion of the 6-chloro moiety to a hydroxy moiety (i.e. to form a guanine) or hydrogen (to form a 2-aminopurine), respectively; and 2-acetoxymethyl-4-halo-butyl-1-yl acetates.

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