Drug – bio-affecting and body treating compositions – Designated organic active ingredient containing – Heterocyclic carbon compounds containing a hetero ring...
Patent
1990-08-01
1991-06-18
Gerstl, Robert
Drug, bio-affecting and body treating compositions
Designated organic active ingredient containing
Heterocyclic carbon compounds containing a hetero ring...
540302, C07D48704, A61K 3140
Patent
active
050250078
ABSTRACT:
Carbapenems of the formula ##STR1## wherein either the 2-fluoren-9-one or 3-fluoren-9-one is attached at the 2-position of the carbapenem are useful antibacterial agents.
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patent: 4543257 (1985-09-01), Cama et al.
L. D. Cama et al., Total Synthesis of Thienamycin Analgos-III, Tetrahedron 39, 2531 (1983).
R. N. Guthikonda, et al., Structure Activity Relationships in the 2-Arylcarbapenem Series, J. Med. Chem., 30, 871 (1987).
Cama Lovji D.
DiNinno Frank P.
Greenlee Mark L.
Heck James V.
Gerstl Robert
Harbour John W.
Merck & Co. , Inc.
Nicholson William H.
Pfeiffer Hesna J.
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